REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

POLN

polymerase (DNA directed) nu

On chromosome: 4p16.3
Known also as: POL4P;


NCBI Gene ID: 353497
NCBI Ensembl Id: ENSG00000130997
MIM Id: (from NCBI OMIM database) 610887
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Arana ME, Takata K, Garcia-Diaz M, Wood RD, Kunkel TA A unique error signature for human DNA polymerase nu. DNA Repair (Amst) Jan. 4, 2007
Zietlow L, Smith LA, Bessho M, Bessho T Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links. Biochemistry Dec. 15, 2009
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Mol Med Jan. 1, 2010
Moldovan GL, Madhavan MV, Mirchandani KD, McCaffrey RM, Vinciguerra P, D'Andrea AD DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol Cell Biol Jan. 1, 2010
Yamanaka K, Minko IG, Takata K, Kolbanovskiy A, Kozekov ID, Wood RD, Rizzo CJ, Lloyd RS Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Chem Res Toxicol March 15, 2010

Last modification of this entry: Oct. 6, 2010.

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