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Bujnicki Lab Homepage

Nbn

nibrin

On chromosome: 4
Known also as: Nbs1;


NCBI Gene ID: 27354
NCBI Ensembl Id: ENSMUSG00000028224
Species: Mus musculus

Mus musculus nibrin (Nbn).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A Genomic instability in mice lacking histone H2AX. Science May 3, 2002
Weiss RS, Leder P, Vaziri C Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Mol Cell Biol Jan. 1, 2003
Dumon-Jones V, Frappart PO, Tong WM, Sajithlal G, Hulla W, Schmid G, Herceg Z, Digweed M, Wang ZQ Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res Nov. 1, 2003
Frappart PO, Tong WM, Demuth I, Radovanovic I, Herceg Z, Aguzzi A, Digweed M, Wang ZQ An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nat Med May 1, 2005

Last modification of this entry: Oct. 6, 2010.

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