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POLR2K

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

On chromosome: 8q22.2
Known also as: RPB12; RPABC4; RPB7.0; hRPB7.0; hsRPB10a; RPB10alpha; ABC10-alpha;


NCBI Gene ID: 5440
NCBI Ensembl Id: ENSG00000147669
MIM Id: (from NCBI OMIM database) 606033
Species: Homo sapiens

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq]


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Shpakovski GV, Acker J, Wintzerith M, Lacroix JF, Thuriaux P, Vigneron M Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. Mol Cell Biol Sept. 1, 1995
Holstege FC, Fiedler U, Timmers HT Three transitions in the RNA polymerase II transcription complex during initiation. EMBO J Dec. 15, 1997
Zhou Z, Licklider LJ, Gygi SP, Reed R Comprehensive proteomic analysis of the human spliceosome. Nature Sept. 12, 2002

Last modification of this entry: Oct. 6, 2010.

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