REPAIRtoire - a database of DNA repair pathways

Welcome! Click here to login or here to register.
Home
Proteins
DNA damage
Diseases
Homologs
Pathways
Keywords
Publications
Draw a picture
 
Search
 
Links
Help
Contact





Bujnicki Lab Homepage

phr

Unnamed Gene ID: 947005

Known also as: ECK0697; JW0698; phrB;


NCBI Gene ID: 947005
Species: Escherichia coli strain K-12 substr. MG1655

The flavoprotein DNA photolyase uses light to repair cyclobutylpyrimidine dimers in DNA. [More information is available at EcoGene: EG10736]. Exposing Escherichia coli to UV radiation at wavelengths near the absorption maximum of DNA produces cyclobutane-type pyrimidine dimers (CPDs) as well as, to a lesser degree, 6-4 pyrimidine-pyrimidones in its DNA. [More information is available at EcoCyc: EG10736].


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Sancar GB, Smith FW, Sancar A Identification and amplification of the E. coli phr gene product. Nucleic Acids Res Oct. 11, 1983
Husain I, Sancar A Photoreactivation in phr mutants of Escherichia coli K-12. J Bacteriol June 1, 1987
Li YF, Sancar A Active site of Escherichia coli DNA photolyase: mutations at Trp277 alter the selectivity of the enzyme without affecting the quantum yield of photorepair. Biochemistry June 19, 1990
Lorence MC, Maika SD, Rupert CS Physical analysis of phr gene transcription in Escherichia coli K-12. J Bacteriol Nov. 1, 1990
Yamamoto K Dissection of functional domains in Escherichia coli DNA photolyase by linker-insertion mutagenesis. Mol Gen Genet March 1, 1992

Last modification of this entry: Oct. 6, 2010.

Add your own comment!

There is no comment yet.
Welcome stranger! Click here to login or here to register.
Valid HTML 4.01! This site is Emacs powered. Made with Django.