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Bujnicki Lab Homepage

MMR: MutSalpha interacts with MutLalpha on heteroduplex DNA with nick 3' to mismatch

[Homo sapiens]


GO molecular function: 0005515



After recognizing the error in DNA, ATP-bound MutS physically interacts with the MutL protein, which then activates a chain of events leading to the repair of the error.


This is the reaction from:
Mismatch in heteroduplex DNA with nick 3' to mismatch bound by MutSalpha in Homo sapiens
to
Mismatch in heteroduplex DNA with nick 3' to mismatch bound by MutSalpha-MutLalpha complex in Homo sapiens


Involved proteins:
Involved enzymes:
Keywords:
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