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Bujnicki Lab Homepage

base mismatch

(base mismatch)





Mismatches appear when two nucleobases, which normally do not form a basepair, appear in opposite strands at the same position in a DNA helix - For example pairs GT or AC.



Sources:

Effects:

Recognizing proteins:
Protein Species
MLH1 Homo sapiens
MSH2 Homo sapiens
MSH6 Homo sapiens
Msh2p Saccharomyces cerevisiae
Msh3p Saccharomyces cerevisiae
MutH Escherichia coli
MutL Escherichia coli
MutS Escherichia coli
SMUG1 Homo sapiens
TDG Homo sapiens


Species:

Is connected with following human diseases:

References:

Authors Title Journal
Kunz C, Saito Y, Schar P DNA Repair in mammalian cells: Mismatched repair: variations on a theme.
-
Cline SD, Hanawalt PC Who's on first in the cellular response to DNA damage? Nat Rev Mol Cell Biol. May 4, 2004

Keywords:

Last modification of this entry: Nov. 11, 2010.

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