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"Identification of two genes immediately downstream from the polA gene of Escherichia coli."

Joyce CM, Grindley ND



Published Dec. 1, 1982 in J Bacteriol volume 152 .

Pubmed ID: 6183253

Abstract:
We have identified two genes within a 1-kilobase region immediately following the polA gene of Escherichia coli. The first, whose transcription is initiated about 150 base pairs beyond the end of the polA coding sequence, is the gene corresponding to the previously sequenced "spot 42 RNA" (B. G. Sahagan and J. E. Dahlberg, J. Mol. Biol. 131:573--592, 1979). The second, located further downstream and transcribed towards polA, is the structural gene for a 22-kilodalton polypeptide, which we have detected by using plasmid-directed protein synthesis in maxicells. Sequence analysis of this region of the E. coli genome suggests that it contains little, if any, redundant DNA.


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Last modification of this entry: Oct. 6, 2010

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