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"Accessory protein function in the DNA polymerase III holoenzyme from E. coli."

O'Donnell M



Published Jan. 1, 1992 in Bioessays volume 14 .

Pubmed ID: 1575709

Abstract:
DNA polymerases which duplicate cellular chromosomes are multiprotein complexes. The individual functions of the many proteins required to duplicate a chromosome are not fully understood. The multiprotein complex which duplicates the Escherichia coli chromosome, DNA polymerase III holoenzyme (holoenzyme), contains a DNA polymerase subunit and nine accessory proteins. This report summarizes our current understanding of the individual functions of the accessory proteins within the holoenzyme, lending insight into why a chromosomal replicase needs such a complex structure.


This publication refers to following REPAIRtoire entries:

Genes
Proteins


Last modification of this entry: Oct. 6, 2010

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