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Brca1

breast cancer 1

On chromosome: 11 60.5 cM

NCBI Gene ID: 12189
NCBI Ensembl Id: ENSMUSG00000017146
Species: Mus musculus

Mus musculus breast cancer 1 (Brca1).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A Genomic instability in mice lacking histone H2AX. Science May 3, 2002
Ganesan S, Silver DP, Greenberg RA, Avni D, Drapkin R, Miron A, Mok SC, Randrianarison V, Brodie S, Salstrom J, Rasmussen TP, Klimke A, Marrese C, Marahrens Y, Deng CX, Feunteun J, Livingston DM BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell Nov. 1, 2002
Aglipay JA, Lee SW, Okada S, Fujiuchi N, Ohtsuka T, Kwak JC, Wang Y, Johnstone RW, Deng C, Qin J, Ouchi T A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway. Oncogene Dec. 4, 2003
Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ Jr, Deng CX Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure. J Biol Chem July 9, 2004
Arlt MF, Xu B, Durkin SG, Casper AM, Kastan MB, Glover TW BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function. Mol Cell Biol Aug. 1, 2004

Last modification of this entry: Oct. 6, 2010.

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