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MGMT

O-6-methylguanine-DNA methyltransferase

On chromosome: 10q26

NCBI Gene ID: 4255
NCBI Ensembl Id: ENSG00000170430
MIM Id: (from NCBI OMIM database) 156569
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Tano K, Shiota S, Collier J, Foote RS, Mitra S Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. Proc Natl Acad Sci U S A Feb. 1, 1990
Rydberg B, Spurr N, Karran P cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells. J Biol Chem June 5, 1990
Mitra S, Kaina B Regulation of repair of alkylation damage in mammalian genomes. Prog Nucleic Acid Res Mol Biol Jan. 1, 1993

Last modification of this entry: Oct. 6, 2010.

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