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COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2
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| Hereditary nonpolyposis colorectal carcinoma is an autosomal dominantly inherited predisposition to develop colorectal cancer, endometrial carcinoma and ovary carcinoma, urinary tract carcinomas, stomach, small bowel and biliary tract carcinoma, and brain tumors. Colorectal carcinoma is characterized by early age at onset, predominantly right sided with an excess of synchrounous and metachronous tumors. HNPCC results from mutations in the MLH1 gene leading to G67E mutation in MLH1 protein. |
DNA repair proteins related with COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2 (#609310) disease:
Following keywords are related to COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2:
Last modification of this entry: Oct. 11, 2010.
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