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nick

(nick)





Special kind of single strand break where the phosphate ester bond is dissolved either on the 5' or 3' side. Nicks can be created enzymatically in the course of repair processes (MMR).



References:

Authors Title Journal
Sancar A, Lindsey-Boltz LA, Unsal-KaƧmaz K, Linn S Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem. Jan. 1, 2004

Keywords:

Last modification of this entry: Oct. 16, 2010.

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