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Bujnicki Lab Homepage

"Selection of a mutant of Escherichia coli which has high mutation rates."

Helling RB



Published Oct. 1, 1968 in J Bacteriol volume 96 .

Pubmed ID: 4879569

Abstract:
A mutation which causes high mutation rates in all other loci tested was induced with nitrosoguanidine and was selected through the ability of the progeny of such mutant cells to mutate to streptomycin resistance at a higher rate than the wild-type cells. This mutation (mut-2) and the Treffers' mutation (mutT1) mapped at approximately the same position to the right of leu. Specificity studies showed that the two mutations differ in rates of mutation produced.


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Last modification of this entry: Oct. 6, 2010

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