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"Renaturation of DNA catalysed by yeast DNA repair and recombination protein RAD10." |
Sung P, Prakash L, Prakash S |
Published Jan. 20, 1992 in Nature volume 355 .
Pubmed ID: 1741062
Abstract:
| The RAD10 gene of Saccharomyces cerevisiae is required for the incision step of excision repair of ultraviolet-damaged DNA, and it functions in mitotic recombination. RAD10 has homology to the human excision repair gene ERCC-1. Here we describe the purification of the protein encoded by RAD10 and show that it is a DNA-binding protein with a strong preference for single-stranded DNA. We also show that RAD10 promotes the renaturation of complementary DNA strands. |
This publication refers to following REPAIRtoire entries:
| Genes |
Last modification of this entry: Oct. 6, 2010
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