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UvrC |
Protein FULL name:
UvrABC system protein C, Excinuclease ABC subunit C.,
Protein SHORT name:
uvrC
UvrC (Escherichia coli strain K-12 substr. MG1655) is product of expression of uvrC gene.
UvrC is involved in:
NER in Escherichia coli strain K-12 substr. MG1655
- UvrD joins the protein-DNA complex in Escherichia coli strain K-12 substr. MG1655
- oligomer and UvrC leaves DNA in ATP-dependent reaction in Escherichia coli strain K-12 substr. MG1655
- UvrC joins UvrB-DNA complex in Escherichia coli strain K-12 substr. MG1655
Keywords:
- transcription-coupled repair NER (TCR-NER)
- nucleotide excision repair (NER)
- response to DNA damage
- global genome repair NER (GGR-NER)
FUNCTION: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity).
SUBUNIT: Interacts with uvrB in an incision complex (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the uvrC family.
SIMILARITY: Contains 1 UVR domain.
| NCBI GenPept GI number(s): |
189038049 |
| Species: | Escherichia coli |
Links to other databases:
| Database | ID | Link |
| Uniprot | A1AC65 |
A1AC65 |
| PFAM: |
PF01541 PF00633 PF02151 PF08459 |
PF01541 PF00633 PF02151 PF08459 |
| InterPro: |
IPR000445 IPR003583 IPR010994 IPR001943 IPR009055 IPR004791 IPR001162 IPR000305 |
IPR000445 IPR003583 IPR010994 IPR001943 IPR009055 IPR004791 IPR001162 IPR000305 |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSN LASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDK SYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFP IRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLS GKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGD DLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGSTELSEVVETFV GQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGD RARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGA DRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRA KVKNTSSLETIEGIGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGL AEKIFWSLKH |
References:
| Title | Authors | Journal |
| The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. | Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK | J Bacteriol April 1, 2007 |
Last modification of this entry: Oct. 19, 2010.
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