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Rad57p

Protein FULL name:

Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p


Rad57p (Saccharomyces cerevisiae) is product of expression of RAD57 gene.



Keywords:



FUNCTION: Participates in the repair of X-ray-induced damage to DNA and in meiosis. It may act in part by stabilizing a repair complex of other RAD genes.

INTERACTION: Q06032:CST9; NbExp=1; IntAct=EBI-14744, EBI-30044; P36156:ECM4; NbExp=1; IntAct=EBI-14744, EBI-2042717; P38953:RAD55; NbExp=1; IntAct=EBI-14744, EBI-14737; P38850:RTT107; NbExp=1; IntAct=EBI-14744, EBI-24788;

SUBCELLULAR LOCATION: Nucleus (Potential).

MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.

SIMILARITY: Belongs to the recA family.


NCBI GenPept GI number(s): 6320207
Species: Saccharomyces cerevisiae

Links to other databases:

Database ID Link
Uniprot P25301 P25301
PFAM: - P25301 (Link - using uniprot id)
InterPro: - P25301 (Link - using uniprot id)
CATH: - -
SCOP: - -
PDB: - -


Protein sequence:
MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLT
LTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECF
TTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGG
LGGKCVYITTEGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQ
EHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYL
DRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWL
VGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYDF
FSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRI
LLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAY
QITKRGIETA

Rad57p (Saccharomyces cerevisiae) belongs to following protein families:
References:

Title Authors Journal
Nucleotide sequence of the RAD57 gene of Saccharomyces cerevisiae. Kans JA, Mortimer RK Gene Aug. 1, 1991
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Jacq C, Alt-Morbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Blocker H, Blugeon C, Boskovic J, Brandt P, Bruckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P, et al. Nature May 1, 1997
Global analysis of protein expression in yeast. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS Nature Oct. 16, 2003


Last modification of this entry: Oct. 6, 2010.

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