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Protein FULL name:
5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family
Protein SHORT name:
ERC11, FEN1, RTH1
Rad27p (Saccharomyces cerevisiae) is product of expression of RAD27 gene.
Rad27p is involved in:
NHEJ in Saccharomyces cerevisiae BER in Saccharomyces cerevisiae
FUNCTION: Single-stranded DNA endonuclease (Probable).
COFACTOR: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding (By similarity).
INTERACTION: P38859:DNA2; NbExp=1; IntAct=EBI-14693, EBI-5973; P47135:JSN1; NbExp=1; IntAct=EBI-14693, EBI-9422; P15873:POL30; NbExp=1; IntAct=EBI-14693, EBI-12993;
SUBCELLULAR LOCATION: Nucleus (Probable).
MISCELLANEOUS: Present with 6120 molecules/cell in log phase SD medium.
SIMILARITY: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Links to other databases:
Rad27p (Saccharomyces cerevisiae) belongs to following protein families:
Last modification of this entry: Oct. 6, 2010.
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