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Heteroduplex DNA with removed mismatch (5' directed MMR)
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Reaction | Previous state | Following state |
ExoI excises erroneous strand some distance beyond the mismatch (5' directed) in Homo sapiens | Heteroduplex DNA with single strand protected by RPA (5' directed, distant site) in Homo sapiens | Heteroduplex DNA with removed mismatch (5' directed MMR) in Homo sapiens |
Reaction | Previous state | Following state |
DNA polymerase delta resynthesizes DNA (5' directed MMR) in Homo sapiens | Heteroduplex DNA with removed mismatch (5' directed MMR) in Homo sapiens | DNA strand being resynthesized by DNA polymerase delta (5' directed MMR) in Homo sapiens |