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Heteroduplex DNA with nick 3' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI
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| Reaction | Previous state | Following state |
| ExoI loads onto heteroduplex DNA with nick 3' to mismatch in Homo sapiens | Mismatch in heteroduplex DNA with nick 3' to mismatch and nicks around mismatch bound by MutSalpha-MutLalpha complex in Homo sapiens | Heteroduplex DNA with nick 3' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI in Homo sapiens |
| Reaction | Previous state | Following state |
| ExoI excises errorenous strand heteroduplex DNA with nick 3' to mismatch in Homo sapiens | Heteroduplex DNA with nick 3' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI in Homo sapiens | Heteroduplex DNA with nick 3' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex and ExoI, with partially excised errorenous strand in Homo sapiens |
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