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damaged base with CH2OH group and ALKBH2
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ALKBH2 removes CH3, CH2OH group from N1 position of purine or N3 of pyrimidine |
Reaction | Previous state | Following state |
ALKBH2 recognises damaged base in Homo sapiens | damaged base in DNA in Homo sapiens | damaged base with CH2OH group and ALKBH2 in Homo sapiens |
Reaction | Previous state | Following state |
ALKBH2 eliminates methyl group from damaged base in Homo sapiens | damaged base with CH2OH group and ALKBH2 in Homo sapiens | native DNA in Homo sapiens |