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DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER]
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Reaction | Previous state | Following state |
Lesion recognition and removal by bifunctional glycosylase in Saccharomyces cerevisiae | damaged DNA with bifunctional glycosylase (with AP lyase activity) [SP-BER] in Saccharomyces cerevisiae | DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER] in Saccharomyces cerevisiae |
Reaction | Previous state | Following state |
Strand scission by APN1/APN2 complex in Saccharomyces cerevisiae | DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER] in Saccharomyces cerevisiae | Scissored DNA strand with APN1/APN2 complex [SP-BER] in Saccharomyces cerevisiae |