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REV3-like, catalytic subunit of DNA polymerase zeta (yeast)

On chromosome: 6q21
Known also as: POLZ; REV3;

NCBI Gene ID: 5980
NCBI Ensembl Id: ENSG00000009413
MIM Id: (from NCBI OMIM database) 602776
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:

Authors Title Journal
Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc Natl Acad Sci U S A June 9, 1998
Hara K, Shimizu T, Unzai S, Akashi S, Sato M, Hashimoto H Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment. Acta Crystallogr Sect F Struct Biol Cryst Commun Dec. 1, 2009
Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Gueranger Q, Glover TW, Canman CE Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol March 1, 2010
Hara K, Hashimoto H, Murakumo Y, Kobayashi S, Kogame T, Unzai S, Akashi S, Takeda S, Shimizu T, Sato M Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. J Biol Chem April 16, 2010
Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC A Large-scale genetic association study of esophageal adenocarcinoma risk. Carcinogenesis July 1, 2010

Last modification of this entry: Oct. 6, 2010.

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