REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

MUS81

MUS81 endonuclease homolog (S. cerevisiae)

On chromosome: 11q13
Known also as: FLJ21012; FLJ44872;


NCBI Gene ID: 80198
NCBI Ensembl Id: ENSG00000172732
MIM Id: (from NCBI OMIM database) 606591
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell July 10, 2009
Munoz IM, Hain K, Declais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol Cell July 10, 2009
Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ, Ruse C, Yates JR 3rd, Russell P, Fuchs RP, McGowan CH, Gaillard PH Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell July 10, 2009
Liu Y, Shete S, Wang LE, El-Zein R, Etzel CJ, Liang FW, Armstrong G, Tsavachidis S, Gilbert M, Aldape K, Xing J, Wu X, Wei Q, Bondy ML Gamma-Radiation Sensitivity and Polymorphisms in RAD51L1 Modulate Glioma Risk. Carcinogenesis July 7, 2010
Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF Variation within DNA repair pathway genes and risk of multiple sclerosis. Am J Epidemiol July 15, 2010

Last modification of this entry: Oct. 6, 2010.

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