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POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa |
Known also as: CDC2; POLD;
| NCBI Gene ID: | 5424 |
| NCBI Ensembl Id: | ENSG00000062822 |
| MIM Id: (from NCBI OMIM database) | 174761 |
| Species: | Homo sapiens |
| The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1, POLD2 (MIM 600815), POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM] |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
References:
| Authors | Title | Journal |
| Dresler SL, Gowans BJ, Robinson-Hill RM, Hunting DJ | Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation. | Biochemistry Aug. 23, 1988 |
| Tsurimoto T, Shinozaki A, Yano M, Seki M, Enomoto T | Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta. | Genes Cells Feb. 1, 2005 |
| Rytkonen AK, Vaara M, Nethanel T, Kaufmann G, Sormunen R, Laara E, Nasheuer HP, Rahmeh A, Lee MY, Syvaoja JE, Pospiech H | Distinctive activities of DNA polymerases during human DNA replication. | FEBS J July 1, 2006 |
Last modification of this entry: Oct. 6, 2010.
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