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CHEK1
CHK1 checkpoint homolog (S. pombe)
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On chromosome: 11q24-q24
Known also as: CHK1;
Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ
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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
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Science
Sept. 5, 1997
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Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H
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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.
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Science
Sept. 5, 1997
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Zhao H, Watkins JL, Piwnica-Worms H
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Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.
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Proc Natl Acad Sci U S A
Nov. 12, 2002
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Arlander SJ, Felts SJ, Wagner JM, Stensgard B, Toft DO, Karnitz LM
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Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.
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J Biol Chem
Jan. 3, 2006
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Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T
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The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
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Mol Cell
Aug. 28, 2009
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Last modification of this entry: Oct. 6, 2010.
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