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XRCC1X-ray repair complementing defective repair in Chinese hamster cells 1 |
Known also as: RCC;
| NCBI Gene ID: | 7515 |
| NCBI Ensembl Id: | ENSG00000073050 |
| MIM Id: (from NCBI OMIM database) | 194360 |
| Species: | Homo sapiens |
| The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq] |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
Last modification of this entry: June 29, 2010.
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