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POLMpolymerase (DNA directed), mu |
Known also as: Tdt-N; Pol Mu; FLJ35482;
| NCBI Gene ID: | 27434 |
| NCBI Ensembl Id: | ENSG00000122678 |
| MIM Id: (from NCBI OMIM database) | 606344 |
| Species: | Homo sapiens |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
References:
| Authors | Title | Journal |
| Ruiz JF, Lucas D, Garcia-Palomero E, Saez AI, Gonzalez MA, Piris MA, Bernad A, Blanco L | Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. | Nucleic Acids Res Jan. 1, 2004 |
| Nick McElhinny SA, Havener JM, Garcia-Diaz M, Juarez R, Bebenek K, Kee BL, Blanco L, Kunkel TA, Ramsden DA | A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. | Mol Cell Aug. 5, 2005 |
| Juarez R, Ruiz JF, Nick McElhinny SA, Ramsden D, Blanco L | A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. | Nucleic Acids Res Jan. 1, 2006 |
| Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Mejean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S | Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. | Carcinogenesis May 1, 2009 |
| Andrade P, Martin MJ, Juarez R, Lopez de Saro F, Blanco L | Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ. | Proc Natl Acad Sci U S A Sept. 22, 2009 |
Last modification of this entry: Oct. 6, 2010.
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