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Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
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On chromosome: 7 4.0 cM
Known also as: Ercc-1;
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Mus musculus excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1), transcript variant 1.
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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McWhir J, Selfridge J, Harrison DJ, Squires S, Melton DW
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Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning.
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Nat Genet
Nov. 1, 1993
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Nunez F, Chipchase MD, Clarke AR, Melton DW
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Nucleotide excision repair gene (ERCC1) deficiency causes G(2) arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21.
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FASEB J
June 1, 2000
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Niedernhofer LJ, Essers J, Weeda G, Beverloo B, de Wit J, Muijtjens M, Odijk H, Hoeijmakers JH, Kanaar R
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The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.
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EMBO J
Nov. 15, 2001
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Hsia KT, Millar MR, King S, Selfridge J, Redhead NJ, Melton DW, Saunders PT
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DNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse.
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Development
Feb. 1, 2003
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Prasher JM, Lalai AS, Heijmans-Antonissen C, Ploemacher RE, Hoeijmakers JH, Touw IP, Niedernhofer LJ
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Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice.
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EMBO J
Jan. 23, 2005
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Last modification of this entry: Oct. 6, 2010.
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