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Bujnicki Lab Homepage

Mpg

N-methylpurine-DNA glycosylase

On chromosome: 11 16.0 cM
Known also as: Aag; APNG; Mid1; AI326268; 9830006D05;


NCBI Gene ID: 268395
NCBI Ensembl Id: ENSMUSG00000020287
Species: Mus musculus

Mus musculus N-methylpurine-DNA glycosylase (Mpg).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Engelward BP, Boosalis MS, Chen BJ, Deng Z, Siciliano MJ, Samson LD Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis Jan. 1, 1993
Hang B, Singer B, Margison GP, Elder RH Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc Natl Acad Sci U S A Nov. 25, 1997
Kim J, Matsunaga N, Koyanagi S, Ohdo S Clock gene mutation modulates the cellular sensitivity to genotoxic stress through altering the expression of N-methylpurine DNA glycosylase gene. Biochem Pharmacol Oct. 15, 2009
Jones LE Jr, Ying L, Hofseth AB, Jelezcova E, Sobol RW, Ambs S, Harris CC, Espey MG, Hofseth LJ, Wyatt MD Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis Dec. 1, 2009

Last modification of this entry: Oct. 6, 2010.

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