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Ube2b
ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)
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On chromosome: 11
Known also as: HR6B; Rad6b; mHR6B; E2-14k; 2610301N02Rik;
Mus musculus ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) (Ube2b).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Baarends WM, Wassenaar E, Hoogerbrugge JW, van Cappellen G, Roest HP, Vreeburg J, Ooms M, Hoeijmakers JH, Grootegoed JA
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Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.
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Mol Cell Biol
Jan. 1, 2003
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Roest HP, Baarends WM, de Wit J, van Klaveren JW, Wassenaar E, Hoogerbrugge JW, van Cappellen WA, Hoeijmakers JH, Grootegoed JA
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The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.
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Mol Cell Biol
June 1, 2004
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Baarends WM, Wassenaar E, Hoogerbrugge JW, Schoenmakers S, Sun ZW, Grootegoed JA
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Increased phosphorylation and dimethylation of XY body histones in the Hr6b-knockout mouse is associated with derepression of the X chromosome.
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J Cell Sci
June 1, 2007
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Tasaki T, Sohr R, Xia Z, Hellweg R, Hortnagl H, Varshavsky A, Kwon YT
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Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.
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J Biol Chem
June 22, 2007
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Shekhar MP, Gerard B, Pauley RJ, Williams BO, Tait L
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Rad6B is a positive regulator of beta-catenin stabilization.
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Cancer Res
March 15, 2008
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Last modification of this entry: Oct. 6, 2010.
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