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Ube2b

ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)

On chromosome: 11
Known also as: HR6B; Rad6b; mHR6B; E2-14k; 2610301N02Rik;


NCBI Gene ID: 22210
NCBI Ensembl Id: ENSMUSG00000020390
Species: Mus musculus

Mus musculus ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) (Ube2b).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Baarends WM, Wassenaar E, Hoogerbrugge JW, van Cappellen G, Roest HP, Vreeburg J, Ooms M, Hoeijmakers JH, Grootegoed JA Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase. Mol Cell Biol Jan. 1, 2003
Roest HP, Baarends WM, de Wit J, van Klaveren JW, Wassenaar E, Hoogerbrugge JW, van Cappellen WA, Hoeijmakers JH, Grootegoed JA The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice. Mol Cell Biol June 1, 2004
Baarends WM, Wassenaar E, Hoogerbrugge JW, Schoenmakers S, Sun ZW, Grootegoed JA Increased phosphorylation and dimethylation of XY body histones in the Hr6b-knockout mouse is associated with derepression of the X chromosome. J Cell Sci June 1, 2007
Tasaki T, Sohr R, Xia Z, Hellweg R, Hortnagl H, Varshavsky A, Kwon YT Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. J Biol Chem June 22, 2007
Shekhar MP, Gerard B, Pauley RJ, Williams BO, Tait L Rad6B is a positive regulator of beta-catenin stabilization. Cancer Res March 15, 2008

Last modification of this entry: Oct. 6, 2010.

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