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Tdp1
tyrosyl-DNA phosphodiesterase 1
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On chromosome: 12
Known also as: SCAN1; MLZ-501; AI838772; AW493413; 2810481F14Rik; 4921509N21Rik; E430034L06Rik;
Mus musculus tyrosyl-DNA phosphodiesterase 1 (Tdp1).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF
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Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
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EMBO J
Nov. 14, 2007
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Katyal S, el-Khamisy SF, Russell HR, Li Y, Ju L, Caldecott KW, McKinnon PJ
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TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.
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EMBO J
Nov. 14, 2007
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El-Khamisy SF, Katyal S, Patel P, Ju L, McKinnon PJ, Caldecott KW
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Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin.
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DNA Repair (Amst)
June 4, 2009
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Chiang SC, Carroll J, El-Khamisy SF
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TDP1 serine 81 promotes interaction with DNA ligase IIIalpha and facilitates cell survival following DNA damage.
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Cell Cycle
Jan. 1, 2010
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Last modification of this entry: Oct. 6, 2010.
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