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Bujnicki Lab Homepage

Tdp1

tyrosyl-DNA phosphodiesterase 1

On chromosome: 12
Known also as: SCAN1; MLZ-501; AI838772; AW493413; 2810481F14Rik; 4921509N21Rik; E430034L06Rik;


NCBI Gene ID: 104884
NCBI Ensembl Id: ENSMUSG00000021177
Species: Mus musculus

Mus musculus tyrosyl-DNA phosphodiesterase 1 (Tdp1).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation? EMBO J Nov. 14, 2007
Katyal S, el-Khamisy SF, Russell HR, Li Y, Ju L, Caldecott KW, McKinnon PJ TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO J Nov. 14, 2007
El-Khamisy SF, Katyal S, Patel P, Ju L, McKinnon PJ, Caldecott KW Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin. DNA Repair (Amst) June 4, 2009
Chiang SC, Carroll J, El-Khamisy SF TDP1 serine 81 promotes interaction with DNA ligase IIIalpha and facilitates cell survival following DNA damage. Cell Cycle Jan. 1, 2010

Last modification of this entry: Oct. 6, 2010.

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