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Bujnicki Lab Homepage

Rrm2b

ribonucleotide reductase M2 B (TP53 inducible)

On chromosome: 15
Known also as: p53R2;


NCBI Gene ID: 382985
NCBI Ensembl Id: ENSMUSG00000022292
Species: Mus musculus

Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Guittet O, Hakansson P, Voevodskaya N, Fridd S, Graslund A, Arakawa H, Nakamura Y, Thelander L Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. J Biol Chem Nov. 2, 2001
Kimura T, Takeda S, Sagiya Y, Gotoh M, Nakamura Y, Arakawa H Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nat Genet Aug. 1, 2003

Last modification of this entry: Oct. 6, 2010.

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