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Prkdc
protein kinase, DNA activated, catalytic polypeptide
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On chromosome: 16 9.2 cM
Known also as: scid; slip; DNAPK; DNPK1; HYRC1; XRCC7; DNAPDcs; AI326420; AU019811; DNA-PKcs;
Mus musculus protein kinase, DNA activated, catalytic polypeptide (Prkdc).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Li T, Ramirez K, Palacios R
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Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes.
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Cell Growth Differ
Feb. 1, 1996
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Taccioli GE, Amatucci AG, Beamish HJ, Gell D, Xiang XH, Torres Arzayus MI, Priestley A, Jackson SP, Marshak Rothstein A, Jeggo PA, Herrera VL
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Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity.
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Immunity
Sept. 1, 1998
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Hamer G, Roepers-Gajadien HL, van Duyn-Goedhart A, Gademan IS, Kal HB, van Buul PP, Ashley T, de Rooij DG
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Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86.
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Biol Reprod
March 1, 2003
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Last modification of this entry: Oct. 6, 2010.
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