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On chromosome: 4
Known also as: Nbs1;
Mus musculus nibrin (Nbn).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A
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Genomic instability in mice lacking histone H2AX.
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Science
May 3, 2002
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Weiss RS, Leder P, Vaziri C
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Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.
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Mol Cell Biol
Jan. 1, 2003
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Dumon-Jones V, Frappart PO, Tong WM, Sajithlal G, Hulla W, Schmid G, Herceg Z, Digweed M, Wang ZQ
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Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis.
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Cancer Res
Nov. 1, 2003
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Frappart PO, Tong WM, Demuth I, Radovanovic I, Herceg Z, Aguzzi A, Digweed M, Wang ZQ
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An essential function for NBS1 in the prevention of ataxia and cerebellar defects.
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Nat Med
May 1, 2005
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Last modification of this entry: Oct. 6, 2010.
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