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Chek1
checkpoint kinase 1 homolog (S. pombe)
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On chromosome: 9
Known also as: Chk1; rad27; C85740;
Mus musculus checkpoint kinase 1 homolog (S. pombe) (Chek1).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, Luo G, Carattini-Rivera S, DeMayo F, Bradley A, Donehower LA, Elledge SJ
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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
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Genes Dev
June 15, 2000
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Weiss RS, Leder P, Vaziri C
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Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.
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Mol Cell Biol
Jan. 1, 2003
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Sengupta S, Robles AI, Linke SP, Sinogeeva NI, Zhang R, Pedeux R, Ward IM, Celeste A, Nussenzweig A, Chen J, Halazonetis TD, Harris CC
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Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
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J Cell Biol
Sept. 13, 2004
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Last modification of this entry: Oct. 6, 2010.
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