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Bujnicki Lab Homepage

Nudt1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

On chromosome: 5
Known also as: Mth1;


NCBI Gene ID: 17766
NCBI Ensembl Id: ENSMUSG00000036639
Species: Mus musculus

Mus musculus nudix (nucleoside diphosphate linked moiety X)-type motif 1 (Nudt1).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Kakuma T, Nishida J, Tsuzuki T, Sekiguchi M Mouse MTH1 protein with 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution. J Biol Chem Oct. 27, 1995
Nakabeppu Y, Kajitani K, Sakamoto K, Yamaguchi H, Tsuchimoto D MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides. DNA Repair (Amst) July 13, 2006
Tsuzuki T, Nakatsu Y, Nakabeppu Y Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis. Cancer Sci April 1, 2007
Mikkelsen L, Bialkowski K, Risom L, Lohr M, Loft S, Moller P Aging and defense against generation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA. Free Radic Biol Med Sept. 1, 2009

Last modification of this entry: Oct. 6, 2010.

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