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Bujnicki Lab Homepage

Ercc2

excision repair cross-complementing rodent repair deficiency, complementation group 2

On chromosome: 7 4.0 cM
Known also as: XPD; Ercc-2; AA407812; AU020867; AW240756;


NCBI Gene ID: 13871
NCBI Ensembl Id: ENSMUSG00000030400
Species: Mus musculus

Mus musculus excision repair cross-complementing rodent repair deficiency, complementation group 2 (Ercc2).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
de Boer J, de Wit J, van Steeg H, Berg RJ, Morreau H, Visser P, Lehmann AR, Duran M, Hoeijmakers JH, Weeda G A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy. Mol Cell June 1, 1998
de Boer J, Andressoo JO, de Wit J, Huijmans J, Beems RB, van Steeg H, Weeda G, van der Horst GT, van Leeuwen W, Themmen AP, Meradji M, Hoeijmakers JH Premature aging in mice deficient in DNA repair and transcription. Science May 17, 2002
Andressoo JO, Jans J, de Wit J, Coin F, Hoogstraten D, van de Ven M, Toussaint W, Huijmans J, Thio HB, van Leeuwen WJ, de Boer J, Egly JM, Hoeijmakers JH, van der Horst GT, Mitchell JR Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles. PLoS Biol Oct. 1, 2006
Park JY, Cho MO, Leonard S, Calder B, Mian IS, Kim WH, Wijnhoven S, van Steeg H, Mitchell J, van der Horst GT, Hoeijmakers J, Cohen P, Vijg J, Suh Y Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice. PLoS One Jan. 1, 2008

Last modification of this entry: Oct. 6, 2010.

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