REPAIRtoire - a database of DNA repair pathways

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Xrcc1

X-ray repair complementing defective repair in Chinese hamster cells 1

On chromosome: 7 5.5 cM
Known also as: Xrcc-1; MGC102556;


NCBI Gene ID: 22594
NCBI Ensembl Id: ENSMUSG00000051768
Species: Mus musculus

Mus musculus X-ray repair complementing defective repair in Chinese hamster cells 1 (Xrcc1).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Chen D, Yu Z, Zhu Z, Lopez CD E2F1 regulates the base excision repair gene XRCC1 and promotes DNA repair. J Biol Chem May 1, 2008
Costa S, Pinto D, Pereira D, Rodrigues H, Cameselle-Teijeiro J, Medeiros R, Schmitt F XRCC1 Arg399Gln and RAD51 5'UTR G135C polymorphisms and their outcome in tumor aggressiveness and survival of Portuguese breast cancer patients. Breast Cancer Res Treat May 1, 2008
Reynolds JJ, El-Khamisy SF, Katyal S, Clements P, McKinnon PJ, Caldecott KW Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1. Mol Cell Biol March 1, 2009
Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci Aug. 1, 2009
Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science July 2, 2010

Last modification of this entry: Oct. 6, 2010.

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