REPAIRtoire - a database of DNA repair pathways

Welcome! Click here to login or here to register.
Home
Proteins
DNA damage
Diseases
Homologs
Pathways
Keywords
Publications
Draw a picture
 
Search
 
Links
Help
Contact





Bujnicki Lab Homepage

Mgmt

O-6-methylguanine-DNA methyltransferase

On chromosome: 7 66.0 cM
Known also as: AGT; Agat; AI267024; MGC107020;


NCBI Gene ID: 17314
NCBI Ensembl Id: ENSMUSG00000054612
Species: Mus musculus

Mus musculus O-6-methylguanine-DNA methyltransferase (Mgmt).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Santibanez-Koref M, Elder RH, Fan CY, Cawkwell L, McKie JH, Douglas KT, Margison GP, Rafferty JA Isolation and partial characterization of murine O6-alkylguanine-DNA-alkyltransferase: comparative sequence and structural properties. Mol Carcinog Jan. 1, 1992
Kawate H, Sakumi K, Tsuzuki T, Nakatsuru Y, Ishikawa T, Takahashi S, Takano H, Noda T, Sekiguchi M Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc Natl Acad Sci U S A April 28, 1998
Takagi Y, Takahashi M, Sanada M, Ito R, Yamaizumi M, Sekiguchi M Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. DNA Repair (Amst) Oct. 7, 2003

Last modification of this entry: Oct. 6, 2010.

Add your own comment!

There is no comment yet.
Welcome stranger! Click here to login or here to register.
Valid HTML 4.01! This site is Emacs powered. Made with Django.