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RAD52
RAD52 homolog (S. cerevisiae)
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On chromosome: 12p13-p12.2
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The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq]
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Shen Z, Denison K, Lobb R, Gatewood JM, Chen DJ
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The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues.
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Genomics
Feb. 1, 1995
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Motycka TA, Bessho T, Post SM, Sung P, Tomkinson AE
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Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52.
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J Biol Chem
April 2, 2004
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Last modification of this entry: Oct. 6, 2010.
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