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POLQpolymerase (DNA directed), theta |
Known also as: POLH; PRO0327; DKFZp781A0112;
| NCBI Gene ID: | 10721 |
| NCBI Ensembl Id: | ENSG00000051341 |
| MIM Id: (from NCBI OMIM database) | 604419 |
| Species: | Homo sapiens |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
References:
| Authors | Title | Journal |
| Sharief FS, Vojta PJ, Ropp PA, Copeland WC | Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase. | Genomics July 1, 1999 |
| Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Mejean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S | Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. | Carcinogenesis May 1, 2009 |
| Hussain SK, Mu LN, Cai L, Chang SC, Park SL, Oh SS, Wang Y, Goldstein BY, Ding BG, Jiang Q, Rao J, You NC, Yu SZ, Papp JC, Zhao JK, Wang H, Zhang ZF | Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China. | Cancer Epidemiol Biomarkers Prev Aug. 1, 2009 |
| Lemee F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roche H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C | DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. | Proc Natl Acad Sci U S A July 27, 2010 |
Last modification of this entry: Oct. 6, 2010.
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