REPAIRtoire - a database of DNA repair pathways

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GTF2H4

general transcription factor IIH, polypeptide 4, 52kDa

On chromosome: 6p21.3
Known also as: TFB2; TFIIH;


NCBI Gene ID: 2968
NCBI Ensembl Id: ENSG00000213780
MIM Id: (from NCBI OMIM database) 601760
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Marinoni JC, Roy R, Vermeulen W, Miniou P, Lutz Y, Weeda G, Seroz T, Gomez DM, Hoeijmakers JH, Egly JM Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH. EMBO J March 3, 1997
Kershnar E, Wu SY, Chiang CM Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. J Biol Chem Dec. 18, 1998
Coin F, Oksenych V, Egly JM Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair. Mol Cell April 27, 2007

Last modification of this entry: Oct. 6, 2010.

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