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ogt
Unnamed Gene ID: 945853
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Known also as: ECK1331; JW1329;
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Ogt is the second (after Ada) methyltransferase enzyme for the direct repair of alkylating lesions in Escherichia coli and is responsible the background constitutive alkyl-transfer when the Ada response is not induced. [More information is available at EcoCyc: EG10668].
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Potter PM, Kleibl K, Cawkwell L, Margison GP
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Expression of the ogt gene in wild-type and ada mutants of E. coli.
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Nucleic Acids Res
Oct. 25, 1989
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Wilkinson MC, Potter PM, Cawkwell L, Georgiadis P, Patel D, Swann PF, Margison GP
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Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
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Nucleic Acids Res
Nov. 11, 1989
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Margison GP, Cooper DP, Potter PM
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The E. coli ogt gene.
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Mutat Res
Jan. 1, 1990
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Rebeck GW, Samson L
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Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase.
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J Bacteriol
March 1, 1991
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Harris LC, Potter PM, Margison GP
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Site directed mutagenesis of two cysteine residues in the E. coli ogt O6-alkylguanine DNA alkyltransferase protein.
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Biochem Biophys Res Commun
Aug. 31, 1992
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Last modification of this entry: Oct. 6, 2010.
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