REPAIRtoire - a database of DNA repair pathways

Welcome! Click here to login or here to register.
Home
Proteins
DNA damage
Diseases
Homologs
Pathways
Keywords
Publications
Draw a picture
 
Search
 
Links
Help
Contact





Bujnicki Lab Homepage

POLDIP2

polymerase (DNA-directed), delta interacting protein 2

On chromosome: 17q11.2
Known also as: POLD4; PDIP38; DKFZp586F1524;


NCBI Gene ID: 26073
MIM Id: (from NCBI OMIM database) 611519
Species: Homo sapiens

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. The encoded protein also interacts with proliferating cell nuclear antigen. Some transcripts of this gene overlap in a tail-to-tail orientation with the gene for tumor necrosis factor, alpha-induced protein 1 (TNFAIP1). [provided by RefSeq]


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep Sept. 1, 2000
Bogenhagen DF, Rousseau D, Burke S The layered structure of human mitochondrial DNA nucleoids. J Biol Chem Jan. 8, 2008
Lyle AN, Deshpande NN, Taniyama Y, Seidel-Rogol B, Pounkova L, Du P, Papaharalambus C, Lassegue B, Griendling KK Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ Res July 31, 2009
Grinchuk OV, Motakis E, Kuznetsov VA Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression. BMC Genomics Jan. 1, 2010

Last modification of this entry: Oct. 6, 2010.

Add your own comment!

There is no comment yet.
Welcome stranger! Click here to login or here to register.
Valid HTML 4.01! This site is Emacs powered. Made with Django.