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EME2essential meiotic endonuclease 1 homolog 2 (S. pombe) |
Known also as: gs125; FLJ00151;
| NCBI Gene ID: | 197342 |
| NCBI Ensembl Id: | ENSG00000197774 |
| MIM Id: (from NCBI OMIM database) | 610886 |
| Species: | Homo sapiens |
| EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM] |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
References:
| Authors | Title | Journal |
| Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR | Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. | Hum Mol Genet Jan. 15, 2001 |
| Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Proc Natl Acad Sci U S A Dec. 24, 2002 |
| Ciccia A, Constantinou A, West SC | Identification and characterization of the human mus81-eme1 endonuclease. | J Biol Chem July 4, 2003 |
| Ciccia A, Ling C, Coulthard R, Yan Z, Xue Y, Meetei AR, Laghmani el H, Joenje H, McDonald N, de Winter JP, Wang W, West SC | Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. | Mol Cell Jan. 9, 2007 |
Last modification of this entry: Oct. 6, 2010.
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