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POLR2Kpolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa |
Known also as: RPB12; RPABC4; RPB7.0; hRPB7.0; hsRPB10a; RPB10alpha; ABC10-alpha;
| NCBI Gene ID: | 5440 |
| NCBI Ensembl Id: | ENSG00000147669 |
| MIM Id: (from NCBI OMIM database) | 606033 |
| Species: | Homo sapiens |
| This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq] |
Gene sequence:
| [Download sequence] |
Proteins coded by this gene:
References:
| Authors | Title | Journal |
| Shpakovski GV, Acker J, Wintzerith M, Lacroix JF, Thuriaux P, Vigneron M | Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. | Mol Cell Biol Sept. 1, 1995 |
| Holstege FC, Fiedler U, Timmers HT | Three transitions in the RNA polymerase II transcription complex during initiation. | EMBO J Dec. 15, 1997 |
| Zhou Z, Licklider LJ, Gygi SP, Reed R | Comprehensive proteomic analysis of the human spliceosome. | Nature Sept. 12, 2002 |
Last modification of this entry: Oct. 6, 2010.
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