REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

POLE2

polymerase (DNA directed), epsilon 2 (p59 subunit)

On chromosome: 14q21-q22
Known also as: DPE2;


NCBI Gene ID: 5427
NCBI Ensembl Id: ENSG00000100479
MIM Id: (from NCBI OMIM database) 602670
Species: Homo sapiens

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Wang TS, Hu SZ, Korn D DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha. J Biol Chem Jan. 10, 1984
Wood RD, Shivji MK Which DNA polymerases are used for DNA-repair in eukaryotes? Carcinogenesis April 1, 1997
Li Y, Asahara H, Patel VS, Zhou S, Linn S Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon. J Biol Chem Dec. 19, 1997
Zhou Q, Talvinen K, Sundstrom J, Elzagheid A, Pospiech H, Syvaoja JE, Collan Y Mutations/polymorphisms in the 55 kDa subunit of DNA polymerase epsilon in human colorectal cancer. Cancer Genomics Proteomics Jan. 1, 2009

Last modification of this entry: Oct. 6, 2010.

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