REPAIRtoire - a database of DNA repair pathways

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ATRAD51C

Unnamed Gene ID: 819136

Known also as: F4L23.21; RAD51C;


NCBI Gene ID: 819136
Species: Arabidopsis thaliana

Encodes a protein similar to RAD51C involved in double stranded break repair via homologous recombination. Sensitive to DSB induced by Mitomycin C and gamma irradiation, interacts with Atxrcc3 in yeast two-hybrid assay. Required for female meiosis but not critical for mitosis under normal conditions.


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Osakabe K, Yoshioka T, Ichikawa H, Toki S Molecular cloning and characterization of RAD51-like genes from Arabidopsis thaliana. Plant Mol Biol Sept. 1, 2002
Bleuyard JY, Gallego ME, Savigny F, White CI Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair. Plant J Jan. 1, 2005
Li W, Yang X, Lin Z, Timofejeva L, Xiao R, Makaroff CA, Ma H The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis. Plant Physiol June 1, 2005

Last modification of this entry: Oct. 6, 2010.

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